Phone: 510-450-7977

CHORI Staff Directory
CHORI Intranet



Elevated LDL cholesterol is one of the most well-established risk factors for cardiovascular disease, which is the leading cause of death in the industrialized world. The goal of the Medina Lab is to identify novel molecular mechanisms and pathways, as well as human genetic variation impacting these pathways, which contribute to inter-individual variation in levels of plasma LDL cholesterol as well as response to cholesterol lowering drugs. In particular, we are focused on the role of variation at the level of the transcriptome (or gene expression), investigating how changes in coding and non-coding transcript levels and/or structure modulate cholesterol metabolism. By understanding the molecular and genetic determinants of variation in plasma LDL cholesterol, Dr. Medina hopes to significantly contribute to our understanding of cardiovascular disease risk, development and treatment.




Revised: Thursday, June 6, 2013 5:43 PM


© 2005 Children's Hospital Oakland Research Institute
5700 Martin Luther King Jr Way • Oakland, California 94609
Phone 510-450-7600 • Fax 510-450-7910
Site MapDisclaimer