Terrance Leighton, PhD
An Overview




Our laboratory studies the molecular mechanisms that control postexponential phase gene expression and the molecular evolution of bacterial endospore formation and spore germination. We also study infectious disease biosurveillance of viral/viral and bacterial/viral co-infections using a novel broadband PCR/MS biosensor technology providing broadband identification and quantitation of respiratory viruses (influenza, adenovirus, respiratory syncytial virus, bocavirus, metapneumovirus, SARS) and bacteria (S. pneumonia, H. influenza, M. catarrhalis, S. aureus, N. meningitidis). This project actively addresses the current medical heath surveillance vacuum that constrains the detection of and response to polymicrobial respiratory infections.
Several types of airborne or desiccation resistant microorganisms including spores cause nosocomial infections and communicable disease. We are developing new types of rapid and safe decontamination technologies to eliminate spores and pathogens from hospitals and health care facilities in a single treatment. These technologies have also been adapted for field use in the US Ebola response in West Africa.




Revised: April 17, 2020 2:05 PM


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