Scientists & Staff


Phone: 510-450-7620


Publications, 1999-present

  1. Malhotra K, Malhotra K, Lubin B, Kuypers F. Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors. Biochemical Journal 1999; 344:135-141.
  2. Styles LA, Aarsman AJ, Vichinsky EP, Kuypers FA. Secretory phospholipase A(2) predicts impending acute chest syndrome in sickle cell disease. Blood 2000; 96:3276-8.
  3. de Jong K, Larkin SK, Eber S, Franck PF, Roelofsen B, Kuypers FA. Hereditary spherocytosis and elliptocytosis erythrocytes show a normal transbilayer phospholipid distribution. Blood 1999; 94:319-25.
  4. Fyrst H, Oskouian B, Kuypers FA, Saba JD. The PLB2 gene of Saccharomyces cerevisiae confers resistance to lysophosphatidylcholine and encodes a phospholipase B/lysophospholipase. Biochemistry 1999; 38:5864-71.
  5. Geldwerth D, Helley D, de Jong K, et al. Detection of phosphatidylserine surface exposure on human erythrocytes using annexin V-ferrofluid. Biochem Biophys Res Commun 1999; 258:199-203.
  6. Murad KL, Mahany KL, Brugnara C, Kuypers FA, Eaton JW, Scott MD. Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). Blood 1999; 93:2121-7.
  7. Zhu Y, Paszty C, Turetsky T, et al. Stomatocytosis is absent in "stomatin"-deficient murine red blood cells. Blood 1999; 93:2404-10.
  8. Aarsman AJ, Neys FW, van der Helm HA, Kuypers FA, van den Bosch H. Sera of patients suffering from inflammatory diseases contain group IIA but not group V phospholipase A(2). Biochim Biophys Acta 2000; 1502:257-63.
  9. Manodori AB, Barabino GA, Lubin BH, Kuypers FA. Adherence of phosphatidylserine-exposing erythrocytes to endothelial matrix thrombospondin. Blood 2000; 95:1293-300.
  10. Morris CR, Kuypers FA, Larkin S, Vichinsky E, Styles L. Patterns of arginine and nitric oxide in sickle cell disease patients with vaso-occlusive crisis and acute chest syndrome. J. Pediatric Hematology/Oncology 2000; 22:515-520.
  11. Morris CR, Kuypers FA, Larkin S, et al. Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease. Br J Haematol 2000; 111:498-500.
  12. Singer ST, Wu V, Mignacca R, Kuypers FA, Morel P, Vichinsky EP. Alloimmunization and erythrocyte autoimmunization in transfusion- dependent thalassemia patients of predominantly asian descent. Blood 2000; 96:3369-73.
  13. Styles L, Kuypers FA. The role of secretory phospholipiase A2 in acute chest syndrome. J. Pediatric Hematology/Oncology 2000; 22:515-520.
  14. Chan J, Kwong M, Emerson R, Kuypers FA. Oxidative stress hemolysis in p45NF-E2 deficient mice. Blood 2001; 97:2145-2151.
  15. Friedman J, V R, Derby R, et al. SOD2 knockout fetal liver stemm cells can effectively reconstitute irradiated hosts, but are defective in erythropoiesis. The Journal of Experimental Medicine 2001; 193:925-934.
  16. Partrick D, Moore E, Silliman C, Barnett C, Kuypers F. Secretory phospholipase A2 activity correlates with postinjury multiple organ failure. Critical Care Medicine 2001; May issue, 29:989-993.
  17. de Jong K, Larkin SK, Styles LA, Bookchin RM, Kuypers FA. Characterization of the phosphatidylserine-exposing subpopulation of sickle cells. Blood. 2001;98: 860-867.
  18. de Jong K, Emerson R, Butler H, Narla M, Kuypers FA. Short survival of PS exposing red blood cells in murine sickle cell anemia. Blood. 2001;98: 1577-1584.
  19. de Jong K, Rettig MP, Low PS, Kuypers FA. Protein kinase C activation induces phosphatidylserine exposure on red blood cells. Biochemistry. 2002;41:12562-12567
  20. Fossati-Jimack L, Azeredo da Silveira S, Moll T, Kina T, Kuypers FA, Oldenborg PA, Reininger L, Izui S. Selective increase of autoimmune epitope expression on aged erythrocytes in mice: implications in anti-erythrocyte autoimmune responses. J Autoimmun. 2002;18:17-25
  21. Leavey PJ, Gonzalez-Aller C, Thurman G, Kleinberg M, Rinckel L, Ambruso DW, Freeman S, Kuypers FA, Ambruso DR. A 29-kDa protein associated with p67phox expresses both peroxiredoxin and phospholipase A2 activity and enhances superoxide anion production by a cell-free system of NADPH oxidase activity. J Biol Chem. 2002;277:45181-45187
  22. Manodori AB, Kuypers FA. Altered red cell turnover in diabetic mice. J Lab Clin Med. 2002;140:161-165
  23. Morris CR, Morris SM, Hagar W, van Warmerdam J, Claster S, Kepka-Lenhart D, Machado L, Kuypers FA, Vichinsky E. Arginine Therapy: a new treatment for pulmonary hypertension in sickle cell disease? American Journal of Respiratory and Critical Care Medicine. 2003;In press


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