Peer Reviewed Research Articles, 2003-2006

Harris SL, King WJ, Ferris W and Granoff DM. Age-related disparity in functional activities of human group C serum anticapsular antibodies elicited by meningococcal polysaccharide vaccine.  Infection and Immunity 2003;71:275-286. Abstract

Plested JS., Harris SL, Wright JC, Coull. PA, Makepeace. K., Gidney. MAJ, Brisson. JR, Richards JC, Granoff., D.M.  and Moxon. ER. Highly conserved Neisseria meningitidis inner core lipopolysaccharide epitope, recognized by a monoclonal antibody (MAb L3 B5), confers protection against experimental meningococcal bacteremia.  Journal of Infectious Diseases 2003;187:1223-1234. Abstract

Jodar L, LaForce M.F., Ceccarini C., Aguado T and Granoff D.M. Meningococcal conjugate vaccine for Africa: A model for developing new vaccines for the poorest countries. The Lancet 2003;361:4997-4999. Abstract

Masignani V, Comanducci M, Giuliani M, Bambini S, Adu-Bobie J, Arico B, Brunelli B, Pieri A, Santini L, Savino S, Serruto D, Litt D, Kroll S, Welsch J, Granoff D, Rappuoli RR, and Pizza M.  vaccination against Neisseria meningitidis using three variants of the lipoprotein GNAA1870.  Journal of Experimental Medicine 2003;197:789-799.  Abstract

Harris S, Finn A, and Granoff D.  Disparity in functional activity between serum anticapsular antibodies induced in adults by immunization with an investigational group A and C Neisseria meningitidis-diphtheria toxoid conjugate vaccine and by a polysaccharide vaccine.  Infection and Immunity 2003;71:3402-3408. Abstract

Welsch JA, Moe GR, Rossi R, Adu-Bobie J, Rappouli R and Granoff DM. Antibody to genome-derived Neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity. Journal of Infectious Diseases 2003;188:1730-1740. Abstract

Hou VC, Moe GR, Raad Z, Wuorimaa T and Granoff DM.  Conformational epitopes recognized by protective anti-neisserial surface protein A antibodies.  Infection and Immunity 2003;71: 6844-6849. Abstract

Adu-BobieJ, LupettiP, Brunell B, GranoffD, NoraisN, FerrariG, GrandiG, RappuoliR and Pizza M. GNA33 of Neisseria meningitidis is a lipoprotein required for cell separation, membrane architecture and virulence. Infection and Immunity 2004;72:1914-1919. Abstract

WelschJA, Rossi R, ComanducciM and GranoffDM. Protective Activity of Monoclonal Antibodies to Genome-Derived Neisserial Antigen 1870, a Neisseria meningitidis Candidate Vaccine. Journal of Immunology 2004;172:5602-5611. Abstract

Granoff DM and Harris SL. Protective activity of group C anticapsular antibodies elicited in 2 year-olds by an investigational quadrivalent Neisseria meningitidis-diphtheria toxoid conjugate vaccine.  Pediatric Infectious Disease Journal 2004;23:490-497. Abstract

Ismail AA, Harris SL and Granoff DM. Serum group A anticapsular antibodies in a Sudanese population immunized during a group A epidemic. Pediatric Infectious Disease Journal 2004; 23:748-755. Abstract

Welsch JA and Granoff DM. Naturally-acquired passive protective activity to Neisseria meningitidis group C in the absence of serum bactericidal activity. Infection and Immunity. 2004;72:5903-5909. Abstract

Lottenbach KR, Granoff DM, Barenkamp SJ, Powers DC, Kennedy D, Irby-Moore S, Homan SM, and Mink CAM. Safety and Immunogenicity of Haemophilus influenzae type b polysaccharide or conjugate vaccines in an elderly adult population. Journal of the American Geriatrics Society 2004;52:1883-1887. Abstract

Amir J, Louie L and Granoff DM. Naturally-acquired immunity to group A Neisseria meningitidis. Vaccine. 2005;23:977-983. Abstract

Granoff DM, Morgan A and Welsch JA. Persistence of group C anticapsular antibodies 2 to 3 years after immunization with an investigational quadrivalent Neisseria meningitidis-diphtheria toxoid conjugate vaccine. Pediatric Infectious Disease Journal. 2005;24:132-136.

Moe GM, Dave A and Granoff DM. Epitopes recognized by a non-autoreactive murine anti-N-propionyl meningococcal group B polysaccharide monoclonal antibody.  Infection and Immunity, 2005;73:2123-2128.

Hou VC, Koeberling O, Welsch JA and Granoff DM.  Protective antibody responses elicited by a  meningococcal outer membrane vesicle vaccine with over-expressed genone-derived Neisserial antigen 1870. Journal of Infectious Diseases, 2005; 192:580-590.

Granoff DM, Morgan A and Welsch JA. Immunogenicity of an investigational quadrivalent Neisseria meningitidis-diphtheria toxoid conjugate vaccine in 2-year old children. Vaccine 2005; 23:4307-4314.

Moe GR, Dave A and Granoff DM. Molecular analysis of anti-N-propionyl Neisseria meningitidis group B polysaccharide monoclonal antibodies. Molecular Immunology, In press E publication, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16140379

Vu DM, Kelly D, Heath PT, McCarthy ND, Pollard AJ and Granoff DM. Effectiveness analyses may underestimate protection of infants after group C meningococcal Immunization. Journal of Infectious Diseases, 2006, in press.

Vu DM, Welsch JA, Zuno-Mitchell P, Dela Cruz JV and Granoff DM.  Antibody persistence 3 years after immunization of adolescents with quadrivalent meningococcal conjugate vaccine, Journal of Infectious Diseases, 2006, electronically published February 2006; 821-828.  JID March 15, 2006:193.

Koeberling, O, Welsch, JA, Granoff, DM.  Improved immunogenicity of a H44/76 Group B Outer Membrane Vessicle Vaccine with Over-Expressed Genone-derived Neisserial Antigen 1870.  Accepted 3/27/06 Journal of VACCINE.

Welsch, JA, Ram,S, Granoff, DM  Genome derived Neisserial Antigen 1870 monoclonal antibodies & encapsulated Neisseria Men.  (c1q)  Submitted 3/13/06

Beernink, PT, Leipus, A, Granoff, DM.  Rapid Genetic Typing of Genone-derived Neisserial Antigen 1870, a promising Group B Meningococcal Vaccine Candidate  Submitted 3/13/06

Vu, D,  A W de Boer, L. Danzig, G. Santos, Bridget Canty, Betty Flores  Priming for Immunologic Memory in Adults by Meningococcal Group C Conjugate Vaccination.  Submitted 3/29/06

Chapters, 2003

Granoff DM, Feavers IM and Borrow R. Meningococcal Vaccines. In: Vaccines, Fourth edition. S.A. Plotkin and W.A. Orenstein, Editors. W.B. Saunders Company, Philadelphia.  2003, pp. 959-987.