PEER REVIEWED RESEARCH ARTICLES, 2006-2009

2006
Moe GR, Dave A and Granoff DM. Molecular analysis of anti-N-propionyl Neisseria meningitidis group B polysaccharide monoclonal antibodies. Molecular Immunology 2006;43:1424-1431. PubMed ID 16140379
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Vu DM, Kelly D, Heath PT, McCarthy ND, Pollard AJ and Granoff DM. Effectiveness analyses may underestimate protection of infants after group C meningococcal Immunization. Journal of Infectious Diseases, 2006;194:231-237. PubMed ID 16779730
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Vu DM, Welsch JA, Zuno-Mitchell P, Dela Cruz JV and Granoff DM. Antibody persistence 3 years after immunization of adolescents with quadrivalent meningococcal conjugate vaccine, Journal of Infectious Diseases, 2006, electronically published February 2006; 821-828. Journal of Infectious Diseases 2006:193:821-828. PubMed ID 16479517
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Beernink PT, Leipus A, Granoff DM. Rapid genetic grouping of factor h-binding protein (genome-derived neisserial antigen 1870), a promising group B meningococcal vaccine candidate. Clinical and Vaccine Immunology 2006;13:758-763. PubMed ID 16829612
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Vu DM, de Boer AW, Danzig L, Santos G, Canty B, Flores BM, Granoff DM. Priming for immunologic memory in adults by meningococcal group C conjugate vaccination. Clinical and Vaccine Immunology 2006;13:605-10. PubMed ID 16760316
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Madico G, Welsch JA, Lewis LA, McNaughton A, Perlman DH, Costello CE, Ngampasutadol J, Vogel U, Granoff DM, Ram S. The meningococcal vaccine candidate GNA1870 binds the complement egulatory protein factor H and enhances serum resistance. Journal of Immunology 2006;177:501-510. PubMed ID 16785547
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Giuliani MM, Adu-Bobie J, Comanducci M, Aricò B, Savino S, Santini L, Brunelli B, Bambini S, Biolchi A, Capecchi B, Cartocci E, Ciucchi L, Di Marcello F, Ferlicca F, Galli B, Luzzi E, Masignani V, Serruto D, Veggi D, Contorni M, Morandi M, Bartalesi A, Cinotti V, Mannucci D, Titta F, Ovidi E, Welsch JA, Granoff D, Rappuoli R, Pizza M. A universal vaccine for serogroup B meningococcus. PNAS 2006;103:10834-10839. PubMed ID 16825336
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Bartolini E, Frigimelica E, Giovinazzi S, Galli G, Shaik Y, Genco C, Welsch JA, Granoff DM, Grandi G, Grifantini R. Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection. Molecular Microbiology 2006;60:963-972. PubMed ID 16677307
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2007
Koeberling, O, Welsch, JA, Granoff, DM. Improved immunogenicity of a H44/76 Group B Outer Membrane Vesicle Vaccine with Over-Expressed Genone-derived Neisserial Antigen 1870. Vaccine 2007;25:1912-1920. PubMed ID 16677743
Abstract

Beernink PT, Welsch JA, Harrison LH, Leipus A, Kaplan SL, Granoff DM. Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: implications for the development of a multicomponent group B vaccine. Journal of Infectious Diseases 2007;195:1472-1479. PubMed ID 17436227
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Granoff DM, Pollard AJ. Reconsideration of the use of meningococcal polysaccharide vaccine. Pediatric Infectious Disease Journal 2007;26: 716-722. PubMed ID 17848884
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Flitter BA, Ismail A, Vu D, Granoff DM. Group A antibody persistence five years after meningococcal polysaccharide vaccination in the Sudan. Human Vaccines 2007;3:135-139. PubMed ID 17581284
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Welsch JA, Granoff D. Immunity to Neisseria meningitidis group B in adults despite lack of serum bactericidal antibody. Clinical and Vaccine Immunology 2007;14:1596-1602. PubMed ID 17913865
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2008
Welsch JA, Ram S, Koeberling O, Granoff DM. Complement-dependent synergistic bactericidal activity of antibodies against factor H-binding protein, a sparsely distributed meningococcal vaccine antigen. Journal of Infectious Diseases 2008;197:1053-1061. PubMed ID 18419542
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Plested JS and Granoff DM. Vaccine-induced opsonophagocytic immunity to Neisseria meningitidis group B. Clinical and Vaccine Immunology 2008;15: 799-804. PubMed ID 18353918
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Beernink PT, Granoff DM. Bactericidal antibody responses induced by meningococcal recombinant chimeric factor H-binding protein vaccines. Infection and Immunity 2008;76: 2568-2575. PubMed ID 18362128
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Koeberling O, Seubert AK, Granoff DM. Bactericidal antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed factor H-binding protein and genetically attenuated endotoxin. Journal of Infectious Diseases 2008;198: 262-270. PubMed ID 18505380
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Beernink PT, Welsch JA, Bar-Lev M; Koeberling O, Comanducci M, Granoff DM. Fine antigenic specificity and cooperative bactericidal activity between monoclonal antibodies directed at the meningococcal vaccine candidate factor H-binding protein. Infection and Immunity 2008;76: 4232-4240. PubMed ID 18591239
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2009
Granoff DM, Welsch JA, and Ram S. Binding of complement factor H (fH) to Neisseria meningitidis is specific for human fH and inhibits complement activation by rat and rabbit sera. Infection and Immunity 2009; 77: 764-769. PubMed ID 19047406
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Koeberling O, Giuntini S, Seubert A, and Granoff DM. Meningococcal outer membrane vesicle vaccines derived from mutant strains engineered to express factor H binding proteins from antigenic variant groups 1 and 2. Clinical and Vaccine Immunology 2009;16:156-162. PubMed ID 19109451
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Beernink PT, Caugant DA, Welsch JA, Koeberling O and Granoff DM. Meningococcal factor H binding protein variants expressed by epidemic group A, W-135 strains from Africa. Journal of Infectious Diseases, 2009; 199:1360-1368. PubMed ID 19302008
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Beernink PT, LoPasso C, Angiolillo A, Felici F and Granoff DM. A region of the N-terminal domain of meningococcal factor H binding protein that elicits bactericidal antibody across antigenic variant groups. Molecular Immunology, 2009;46:1647-1653. PubMed ID 19286260.
Abstract

Plested J, Welsch, JA and Granoff DM. An ex-vivo meningococcal human blood bacteremia model for measuring vaccine-induced serum passive protective activity. Clinical and Vaccine Immunology, 2009; 16:785-91. PubMed ID 19339487
Abstract

Granoff DM. The relative importance of bactericidal and opsonic activity for protection against meningococcal disease. Vaccine, 2009; 27 S117-25, PubMed ID 19477054
Abstract

Beernink PT and Granoff DM. A modular architecture of meningococcal factor H-binding protein. Microbiology, 2009; 155:2873-2883. PubMed ID 19574307
Abstract 

Pajon R, Beernink PT, Harrison LH, Granoff DM. Frequence of factor H-binding protein modular groups and susceptibility to cross-reactive bactericidal activity in invasive meningococcal isolates. Vaccine, 2010. PubMed ID 20044056
Abstract

Granoff DM. Review of group B meningococcal vaccines. Clinical Infectious Diseases. In press.

CHAPTERS

Granoff DM, Harrison LH, and Borrow R.  Meningococcal Vaccines.  In: Plotkin SA, Orenstein WA, and Offit PA, editors.  Vaccines, Fifth edition.  Philadelphia: Saunders Elsevier, 2008:399-434

Revised: Wednesday, January 27, 2010 10:41 AM