DAN M. GRANOFF, MD
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: Dan Granoff
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PEER REVIEWED RESEARCH ARTICLES, 2015-2017

2017
Partridge E, Lujan E, Giuntini S, Vu DM, and Granoff DM. The role of anti-NHba antibody in bactericidal activity elicited by the meningococcal serogroup B vaccine, MenB-4C. Vaccine. 2017;Jun 23. doi:10.1016/j.vaccine.2017.06.020.
[Epub ahead of print]. PubMed ID: 28651840.
Abstract

Konar M, and Granoff DM. Eculizumab blocks vaccine-induced opsonophagocytic killing of meningococci by whole blood from immunized adults. Blood. 2017;Jun 19. doi:10.1182/blood-2017-05-781450. [Epub ahead of print]. PubMed ID: 28630122.
Abstract

Lujan E, Winter K, Rovaris J, Liu Q, and Granoff DM. Serum bactericidal antibody responses of students immunized with a meningococcal serogroup B vaccine in response to an outbreak on a university campus. Clinical Infectious Diseases 2017;
Jun 3. doi:10.1093/cid/cix519. [Epub ahead of print]. PubMed ID: 28582542.
Abstract

Lujan E, Partridge E, Giuntini S, Ram S, and Granoff DM. Breadth and duration of meningococcal serum bactericidal activity in healthcare workers and microbiologists immunized with the MenB-FHbp vaccine. Clinical Vaccine and Immunology 2017; doi:10.1128/CVI.00121-17. [Epub ahead of print]. PubMed ID: 28566335.
Abstract

Giuntini S, Lujan E, Gibani MM, Dold C, Rollier CS, Pollard AJ and Granoff DM. Serum bactericidal antibody responses of adults immunized with the MenB-4C vaccine against genetically diverse serogroup B meningococci. Clinical Vaccine and Immunology 2017;5:e00430. PubMed ID: 27847367.
PDF

2016
Granoff DM, Giuntini S, Gowans FA, Lujan E, Sharkey K, and Beernink PT. Enhanced protective antibody to a mutant meningococcal factor H-binding protein with low-factor H binding. Journal of Clinical Investigation Insight 2016;1:e88907.
PubMed ID: 27668287.
PDF

Giuntini S, Granoff DM, Beernink PT, Ihle O, Bratlie D, and Michaelsen TE. Human IgG1, IgG3, and IgG3 hinge-truncated mutants show different protection capabilities against meningococci depending on the target antigen and epitope specificity. Clinical Vaccine and Immunology 2016;23:698-706. PubMed ID: 27307451.
PDF

Pajon R, Lujan E, and Granoff DM. A meningococcal NOMV-FHbp vaccine for Africa elicits broader serum bactericidal antibody responses against serogroup B and non-B strains than a licensed serogroup B vaccine. Vaccine 2016;34:643-649.
PubMed ID: 26709637.
PDF

2015
Rossi R, Beernink PT, Giuntini S, and Granoff DM. Susceptibility of meningococcal strains responsible for two serogroup B outbreaks on U.S. university campuses to serum bactericidal activity elicited by the MenB-4C vaccine. Clinical Vaccine and Immunology 2015;22:1227-1234. PubMed ID: 26424832.
PDF

Giuntini S, Beernink PT, and Granoff DM. Effect of complement Factor H on anti-FHbp serum bactericidal antibody responses of infant rhesus macaques boosted with a licensed meningococcal serogroup B vaccine. Vaccine 2015;33:7168-7175. PubMed ID: 26562320.
Abstract

Lujan E, Pajon R, and Granoff DM. Impaired immunogenicity of meningococcal neisserial surface protein A in human complement factor H transgenic mice. Infection and Immunity 2015;84:452-458. PubMed ID: 26597984.
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Granoff DM, Costa I, Konar M, Giuntini S, Van Rompay KK and Beernink PT. Binding of complement factor H (FH) decreases protective anti-FH binding protein antibody responses of infant rhesus macaques immunized with a meningococcal serogroup B vaccine. Journal of Infectious Diseases 2015;212:784-792. PubMed ID: 25676468.
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Konar M, Beernink PT, and Granoff DM. A newly-identified polymorphism in rhesus macaque complement factor H modulates binding affinity for meningococcal FHbp. PLoS One 2015;10:e0135996. PubMed ID: 26285122.
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Beernink PT, Giuntini S, Costa I, Lucas AH and Granoff DM. Functional analysis of the human antibody response to meningococcal factor H binding protein. mBio 2015;6:e00842. PubMed ID: 26106082.
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Giuntini S, Pajon R, Ram S and Granoff DM. Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity. Infection and Immunity 2015;83:1536-1545. PubMed ID: 25644002.
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Pajon R, Buckwalter CM, Johswich KO, Gray-Owen SD and Granoff DM. A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice. Vaccine 2015;33:1317-1323. PubMed ID: 25662856.
PDF

CHAPTERS
Granoff DM, Pelton S, and Harrison LH. Meningococcal vaccines. In: Plotkin SA, Orenstein WA, and Offit PA, editors. Vaccines. 6th ed. Philadelphia: Saunders Elsevier; 2013. p 388-418.

Granoff DM and Gilsdorf JR. Neisseria meningitidis (Meningococcus). In:  Kliegman RM, Stanton B, St. Geme J, Schor N, and Behrman RE, editors. Nelson Textbook of Pediatrics. 19th ed. Philadelphia: Saunders Elsevier; 2012. p 929-935.

Revised: Thursday, July 6, 2017 9:45 AM

 


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