Publications

Contact hfischer@chori.org for reprint requests of these articles or other inquiries.
Click here for articles published in the 1980s, 1990s

Illek B, Lizarzaburu ME, Lee V, Nantz MH, Kurth MJ, Fischer H (2000) Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin. Am J Physiol Cell Physiol 279, C1838-C1846. Abstract
        
Fischer H, Fukuda N, Barbry P, Illek B, Sartori C, Matthay MA (2001) Partial restoration of defective chloride conductance in DF508 CF mice by trimethylamine oxide. Am J Physiol Lung Cell Mol Physiol 281, L52-L57. Abstract
         
Fischer H, Widdicombe JH, Illek B (2002) Acid secretion and proton conductance in human airway epithelium. Am J Physiol Cell Physiol 282, 736-743. Abstract
   
Fischer H (2002) Electrophysiological approach to studying CFTR. In:  Methods in Molecular Medicine, Cystic Fibrosis Methods and Protocols. Ed. WR Skatch. Humana Press Inc., Totowa, 49-66.

Chung NC, Illek B, Widdicombe JH, Fischer H (2003) Measurement of nasal potential difference in asthmatics. Chest 123, 1467-1471. Abstract          

Howard M, Fischer H,  Roux J, Santos BC, Gullans SR, Yancey PH, Welch WJ. (2003) Mammalian osmolytes and S-nitrosoglutathione promote DF508 cystic fibrosis transmembrane conductance regulator (CFTR) protein maturation and function. J Biol Chem 278, 35159-35167. Abstract

Fischer H, Schwarzer C, Illek B (2004) Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel. Proc Natl Acad  Sci USA  101, 3691-3696. Abstract

Fischer H, Machen TE, Widdicombe JH, Carlson TJS, Chow JWS, Illek B (2004) A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells. J Ethnopharmacology 93, 351-357. Abstract

Schwarzer C, Machen TE, Illek B, Fischer H (2004) NADPH oxidase-dependent acid production in airway epithelial cells. JBiol Chem 279, 36454-36461. Abstract

Tong Z, Illek B, Bhaghwandin VJ,  Verghese GM, Caughey GH (2004) Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in cystic fibrosis airway epithelia. Am J Physiol Lung Cell Mol Physiol 287, L928-935. Abstract

Fischer H, Illek B (2005) Vitamin C and flavonoids potentiate Cl secretion across airway epithelia. In: Defects of Secretion in Cystic Fibrosis. Adv Exp Med Biol Vol. 558, Ed.Schultz C. Kluwer Academic/Plenum Publisher, 129-143.

Schuier M, Sies H, Illek B, Fischer H (2005) Cocoa-related flavonoids inhibit CFTR-mediated chloride transport across T84 human colon epithelia.  J Nutr 135,2320-2325. Abstract

Fischer H, Widdicombe JH (2006) Mechanisms of acid and base secretion by the airway epithelium. J Membr Biol 211, 139-150. Abstract

Gaggioli V, Schwarzer C, Fischer H (2007) Expression of Nox1 increases cellular acid production but not proton conductance. Arch Biochem Biophys  459, 189-196. Abstract

Fischer H, Illek B, Finkbeiner WE, Widdicombe JH (2007) Basolateral Cl channels in primary airway epithelial cultures. Am J Physiol Lung Cell Mol Physiol 292, L1432-L1443. Abstract

Fischer H, Gonzales LK, Kolla V, Schwarzer C, Miot F, Illek B, Ballard PL (2007) Developmental regulation and function of Duox1 in fetal lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 292, L1506-L1514. Abstract

Schwarzer C, Illek B, Suh JH, Remington SJ, Fischer H, Machen TE (2007) Organelle redox of CF and CFTR-corrected airway epithelia. Free Radic Biol Med 43, 300-316. Abstract

Fischer H (2007) Airway surface liquid pH and innate defense by the NADPH
oxidase. Ped Pulmonol suppl 30, 175-177.

Wagner JG, Jiang Q, Harkema JR, Illek B, Patel DD, Ames BN, Peden DB (2007) Ozone enhancement of lower airway allergic inflammation is prevented by
g-tocopherol. Free Radic Biol Med 43, 1176-1188. Abstract

Rajagopal M, Fischer H, and Widdicombe JH (2008) Hormonal and purinergic stimulation of bicarbonate secretion in oviducts of rhesus monkey. Am J Physiol Endocrinol Metab., in press. Abstract

Cloned Genes

Schwarzer C, Machen TE, Illek B, Fischer H (2003) Homo sapiens NADPH oxidase 4 variant (Nox4) mRNA. GenBank Acc No. AY288918. Abstract

Schwarzer C, Borcanski G, Widdicombe JH, Fischer H, Illek B (2003)  SVCT2 in ciliated human tracheal epithelial cultures. GenBank Acc No. AY380556. Abstract

Revised: April 23, 2008