Giorgio Cavigiolio PhD
An Overview
Scientists and Staff


Phone: 510-450-7630
Fax: 510-450-7910



(* corresponding authors, # both authors equally contributed)

Andrzej Witkowski, Sonia Carta, Rui Lu, Shinji Yokoyama, Anna Rubartelli, and Giorgio Cavigiolio*, Oxidation of methionine residues in human apolipoprotein A I generates a potent pro inflammatory molecule, Journal of Biological Chemistry, 2019, 294 (10), 3634-3646. Article

Andrzej Witkowski#, Gary K. L. Chan#, Nancy Jingyi Li, Ayuka Patricia Inoue, Jaclyn C. Wong, Jennifer C. Boatz, Patrick C. A. van der Wel, and Giorgio Cavigiolio*, Methionine Oxidized Apolipoprotein A-I at the Crossroads of HDL Biogenesis and Amyloid Formation, FASEB Journal, 2018, 32 (6), 3149-3165. Article

Aparna Krishnamoorthy, Narjes Tavoosi, Gary K. L. Chan, Jianfang Liu, Gang Ren, Giorgio Cavigiolio*, and Robert O. Ryan*, Effect of Curcumin on Amyloid-like Aggregates Generated from Methionine-Oxidized Apolipoprotein A-I, FEBS Open Bio, 2018, 8, 302-310. Article

Gary K. L. Chan, Andrzej Witkowski, Donald L. Gantz, Tianqi O. Zhang, Martin T. Zanni, Shobini Jayaraman, and Giorgio Cavigiolio*, Myeloperoxidase-mediated Methionine Oxidation Promotes an Amyloidogenic Outcome for Apolipoprotein A-I, Journal of Biological Chemistry, 2015, 290 (17), 10958-10971. Article

Giorgio Cavigiolio* and Shobini Jayaraman*, Proteolysis of Apolipoprotein A-I by Secretory Phospholipase A2. A new Link between Inflammation and Atherosclerosis, Journal of Biological Chemistry, 2014, 289 (14), 10011-10023. Article

Michael N. Oda, Madhu S. Budamagunta, Ethan G. Geier, Sajiv H Chandradas, Baohai Shao, Jay W. Heinecke, John C. Voss, and Giorgio Cavigiolio*, Conservation of Apolipoprotein A-Is Central Domain Structural Elements upon Lipid Association on Different High-Density Lipoprotein Subclasses, Biochemistry, 2013, 52 (39), 67666778. Article

Loren E. Smith#, Jun Yang#, Leah Goodman, Xinqi Huang, Rong Huang, James Dressman, Jamie Morris, R.A. Gangani D. Silva, W. Sean Davidson*, and Giorgio Cavigiolio*, High yield expression and purification of recombinant human apolipoprotein A-II in E. coli, Journal of Lipid Research, 2012, 53 (8), 1708-1715. # Both authors equally contributed. Article

Andrew N. Hoofnagle*, Jessica O. Becker, Michael N. Oda, Giorgio Cavigiolio, Philip Mayer, Tomas Vaisar, Multiple-reaction monitoring-mass spectrometric assays can accurately measure the relative protein abundance in complex mixtures, Clinical Chemistry, 2012, 58 (4), 777-781. Abstract

Lei Zhang#, Feng Yan#, Shengli Zhang, Dongsheng Lei, M. Arthur Charles, Giorgio Cavigiolio, Michael N. Oda, Ronald M. Krauss, Karl H. Weisgraber, Kerry-Anne Rye, Henry J. Pownall, Xiayang Qiu, and Gang Ren*, Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein, Nature Chemical Biology, 2012, 8 (4), 342-349. # Both authors equally contributed. Article

Shobini Jayaraman*, Giorgio Cavigiolio, Olga Gursky*, Folded functional lipid-poor apolipoprotein A-I obtained by heating of high-density lipoproteins: relevance to HDL biogenesis, Biochemical Journal, 2012, 286, 41, 35610-35623. Article

Shobini Jayaraman, Sumiko Abe-Dohmae, Shinji Yokoyama, Giorgio Cavigiolio*, Impact of self-association on function of apolipoprotein A-I, Journal of Biological Chemistry, 2011, 286, 41, 35610-35623. PMCID: PMC3195568. Article

Jens Lagerstedt#, Giorgio Cavigiolio#, Madhu S. Budamagunta, Ioanna Pagani, John C. Voss, Michael N. Oda*, Structure of apolipoprotein A-I’s N-terminus on nascent high density lipoprotein, Journal of Biological Chemistry, 2011, 286, 4, 2966-2975. PMCID: PMC3024791. # Both authors equally contributed. Article

Lei Zhang#, James Song#, Giorgio Cavigiolio, Brian Y. Ishida, Shengli Zhang, John P. Kane, Karl H. Weisgraber, Michael N. Oda, Karry-Anne Rye, Henry J. Pownall, Gary Ren*, Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy, Journal of Lipid Research, 2011, 52, 1, 175-184. PMCID: PMC2999936. # Both authors equally contributed. Article

Giorgio Cavigiolio*, Ethan G. Geier, Baohai Shao, Jay W. Heinecke, Michael N. Oda*, The exchange of apolipoprotein A-I between lipid-associated and lipid-free states, a potential target for oxidative generation of dysfunctional high density lipoproteins, Journal of Biological Chemistry, 2010, 285, 24, 18847-18857. PMCID: PMC2881807. Article

Kathleen A. Smoak, Jim J. Aloor, Jennifer Madenspacher, B. Alex Merrick, Jennifer B. Collins, Xuewei Zhu, Giorgio Cavigiolio, Michael N. Oda, John S. Parks, Michael B. Fessler*, Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation, Cell Metabolism, 2010, 11, 6, 493-502. PMCID: PMC3091482. Article

Braydon L. Burgess, Giorgio Cavigiolio, Michelle V. Fannucchi, Beate Illek, Trudy M. Forte, Michael N. Oda*, A phospholipid-apolipoprotein-AI nano-particle containing amphotericin B as a drug delivery platform with cell membrane protective properties, International Journal of Pharmaceutics, 2010, 399, 1-2, 148-155. PMCID: PMC2946961. Article

Vincent Oliéric, Philippe Wolff, Akiko Takeuchi, Guillaume Bec, Catherine Birck, Marc Vitorino, Bruno Kieffer, Artemy Beniaminov, Giorgio Cavigiolio, Elizabeth Theil, Christine Allmang, Alain Krol and Philippe Dumas*, SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein, Biochimie, 2009, 91, 8, 1003-1009. Article

Giorgio Cavigiolio, Baohai Shao, Ethan G. Geier, Gang Ren, Jay W. Heinecke, and Michael N. Oda*, The interplay between size, morphology, stability, and functionality of high-density lipoprotein subclasses, Biochemistry, 2008, 47, 16, 4770–4779. PMCID: PMC2902722. Article

Baohai Shao, Giorgio Cavigiolio, Nathan Brot, Michael N. Oda, Jay W. Heinecke*, Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I, Proceedings of the National Academy of Science of the United States of America, 2008, 105, 34, 12224-12229. PMCID: PMC2527893. Article

Jens Lagerstedt, Giorgio Cavigiolio, Linda Roberts, Hyun-Seok Hong, Lee-Way Jin, Paul Fitzgerald, Michael N. Oda, and John Voss*, Mapping the structural transition in an amyloidogenic apolipoprotein A-I, Biochemistry, 2007, 46, 9693-9699. Article

Helen C. Poynton, Julia R. Varshavsky, Bonnie Chang, Giorgio Cavigiolio, Sarah Chan, Patricia S. Holman, Alexandre V. Loguinov, Darren J. Bauer, Kelly Komachi, Elizabeth C. Theil, Edward J. Perkins, Owen Hughes, and Chris D. Vulpe*, Daphnia magna ecotoxicogenomics provides mechanistic insights into metal toxicity, Environmental Science and Technology, 2007, 41 (3), 1044-1050. Article

Anna I. Selezneva, Giorgio Cavigiolio, Elizabeth C. Theil, William E. Walden, and Karl Volz*, Crystallization and preliminary x-ray diffraction analysis of iron regulatory protein-1 in complex with ferritin IRE RNA, Acta Crystallografica, 2006, F62, 249-252. PMCID: PMC2197192. Article

Domenico Osella*, Homa Mahboobi, Donato Colangelo, Giorgio Cavigiolio, Anne Vessières, and Gérard Jaouen, FACS analysis of oxidative stress induced on tumour cells by SERMs, Inorganica Chimica Acta, 2005, 358, 1993-1998. Article

Carlo Nervi, Marco A. Vigna, Giorgio Cavigiolio, Mauro Ravera, and Domenico Osella*, Synthesis and characterization of functionalized thymidine as a potential carrier for cisplatin-like drugs, Inorganica Chimica Acta, 2005, 358, 2799-2803.

Giorgio Cavigiolio, Joy L. Morgan, Brian H. Robinson*, and Jim Simpson, Fluorescent sugar and uridine conjugates of 1,8-naphthalimides with methyl and ferrocenyl headgroups, Australian Journal of Chemistry, 2004, 57, 885-894Article

Donato Colangelo, Anna Lisa Ghiglia, Ilario Viano, Giorgio Cavigiolio, and Domenico Osella*, Cis-[Pt(Cl)2(pyridine)(5-SO3H-isoquinoline)] complex, a selective inhibitor of telomerase enzyme, BioMetals, 2003, 16, 553-560. Article

Giovanni Tabbì, Claudio Cassino, Giorgio Cavigiolio, Donato Colangelo, Anna Lisa Ghiglia, Ilario Viano, and Domenico Osella*, Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process, Journal of Medicinal Chemistry, 2002, 45, 5786-5796. Article

Domenico Osella*, Francesco Galeotti, Giorgio Cavigiolio, Carlo Nervi, Kenneth I. Hardcastle, Anne Vessières, and Gérard Jaouen, The hexacarbonyl(ethyne)dicobalt unit: an androgen tag, Helvetica Chimica Acta, 2002, 85 (9), 2918-2925. Abstract

Domenico Osella*, Carlo Nervi, Francesco Galeotti, Giorgio Cavigiolio, Anne Vessières, and Gérard Jaouen*, The ferrocenylethynyl unit: a stable hormone tag, Helvetica Chimica Acta, 2001, 84, 3289-3298. Abstract

Giorgio Cavigiolio, Luigina Benedetto, Enrico Boccaleri, Donato Colangelo, Ilario Viano, and Domenico Osella*, Pt(II) complexes with different nitrogen ligands as models for specific inhibition of telomerase, Inorganica Chimica Acta, 2000, 305, 61-68. Article

Domenico Osella*, Marco Ferrali, Piero Zanello, Franco Laschi, Marco Fontani, Carlo Nervi, and Giorgio Cavigiolio, On the mechanism of the antitumor activity of ferrocenium derivatives, Inorganica Chimica Acta, 2000, 306, 42-48. Article

Domenico Osella, Giorgio Cavigiolio, Marco Vincenti, Anne Vessières, Ioanna Laios, Guy Leclercq, Elio Napolitano, Rita Fiaschi, and Gérard Jaouen*, The first organometallic derivative of 11b-ethynylestradiol, a potential high-affinity marker for the estrogen receptor, Journal of Organometallic Chemistry, 2000, 595, 242-247. Article

Domenico Osella*, Mauro Ravera, Carlo Nervi, Giorgio Cavigiolio, Marco Vincenti, Anne Vessières, and Gérard Jaouen*, Stabilization of carbenium ions derived from ethynylestradiol by different adjacent organometallic moieties. Implication in the inactivation of the estrogen receptor, European Journal of Inorganic Chemistry, 2000, 491-497. Abstract

Revised: Wednesday, September 25, 2019 12:41 PM


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