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2010 CHORI Research Symposium
Celebrating 50 Years of Research


Helen H. Hobbs
Howard Hughes Medical Institute and McDermott Center, University of Texas Southwestern Medical Center, Dallas, TX

Talk Title:
Genetic protection from diseases of dietary excess



Insufficient time has elapsed for our genomes to adapt to the caloric abundance and reduced physical activity accompanying industrialization. Diseases of dietary excess, rather than nutritional deficiency are the major causes of death and disability in the Western world. Using human genetics, we have identified new genes and sequence variations conferring susceptibility (and resistance) to metabolic disorders associated with diabetes and heart disease


Helen H. Hobbs is an Investigator of the Howard Hughes Medical Institute and a Professor of Internal Medicine and Molecular Genetics at the University of Texas (UT) Southwestern Medical Center.  She graduated Stanford University and Case Western Reserve University School of Medicine.  She obtained clinical training in internal medicine at Columbia-Presbyterian Medical Center and the University of Texas Southwestern Medical Center in Dallas, Texas. She joined the faculty of UT Southwestern in 1987 and is currently Director of the McDermott Center for Human Growth and Development as well as the Dallas Heart Study. Her work focuses on defining genetic variations that contribute to susceptibility to metabolic and cardiovascular diseases. She is a member of the Institute of Medicine, the American Academy of Arts and Sciences, and the National Academy of Sciences.




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