January, 2013 – CHORI is pleased to announce that CHORI Assistant Scientist and Pediatric Infectious Disease Physician at Children’s Hospital, A. Desiree LaBeaud, MD, will receive funding through the Bill & Melinda Gates Foundation’s Grand Challenges in Global Health Initiative to study the role of parasitic infections in poor vaccine response in children in developing countries.
The Initiative was launched to overcome persistent bottlenecks that prevent the creation of new and better health solutions for the developing world. Dr. LaBeaud’s research will be funded through the Initiative’s newly formed Achieving Healthy Growth program, which seeks to discover the causes of faltering growth during the first 1,000 days of life and to identify effective and affordable interventions to promote healthy growth.
|“Information from our study will be important for current parasite treatment programs, global vaccination programs, and future vaccine trials.”
"Children in developing countries do not always respond appropriately to life-saving vaccines , and many factors may be responsible for this poor vaccination response, such as malnutrition and HIV, but chronic parasitic infections also play a role," says Dr. LaBeaud, who is partnering with researchers at Case Western Reserve University in Cleveland, Ohio and the Division of Vector Borne and Neglected Diseases of the Kenyan Ministry of Public Health and Sanitation.
The project, entitled "Enhancing Infant Immunity: Effect of Early Maternal Treatment for Parasitic Infections," will determine how parasitic infections in pregnant mothers affect the function of the fetal immune system, the mechanism for this effect, and whether earlier prenatal parasitic treatment can reverse the harmful effects.
"Information from our study will be important for current parasite treatment programs, global vaccination programs, and future vaccine trials," said Dr. LaBeaud.
Dr. LaBeaud's project is one of only eight grants awarded worldwide in the Healthy Growth Initiative, andtakes advantage of the considerable resources and expertise at Children's Hospital Oakland Research Institute, Case Western Reserve University, and the Division of Vector Borne and Neglected Diseases of the Kenyan Ministry of Public Health and Sanitation.
"Our planned research may lead to specific interventions that could improve vaccination responses in children in developing countries," says Dr. LaBeaud.
|“We hope that our research along with others in the Healthy Growth Initiative will provide data to enable global policy changes that significantly improve child health worldwide.”
Friday, April 12, 2013 7:39 AM