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Translating Results from the Lab to the Clinic
New Scientist Joins CHORI

February, 2012 - CHORI is pleased to announce that Associate Scientist Wen-Shu Wu, PhD has joined the CHORI team. An expert in hematopoietic stem cell renewal and cell-fate determinations, Dr. Wu was recruited from the Maine Medical Research Institute to expand his research in the areas of pluripotent stem cells and genetic reprogramming.

“My broad area of research is on stem cell biology and the development of new tools for use in the application of stem cell therapies for some of the most debilitating conditions, such as cancer, sickle cell disease or thalassemia,” says Dr. Wu.



Dr. Wu has been recruited through CHORI's Jordan Family Center for Blood and Marrow Transplantation and Cellular Therapies Research Endowment. His two ongoing National Institutes of Health (NIH) grants investigate ways to enhance stem cell regeneration following stem cell transplantation. Currently, Dr. Wu has plans to develop novel stem cell therapy for curing blood cell diseases by combining somatic cell reprogramming and genome editing approaches.

While much of Dr. Wu's work has been in the basic laboratory, stem cell research at its heart is about improving the odds for patients whose only recourse for a cure lies in stem cell transplantation. As a result, Dr. Wu was drawn to the Jordan Family Center in particular for its signature translational research approach.

"I was really excited about the opportunity to work in an environment that fosters such wonderful collaborations between basic science and the clinic. While I work in the lab, I want my research to contribute to the development of novel therapies for diseases like sickle cell anemia. Here at CHORI, there is the opportunity to truly bring my work directly into the clinic and the patients who need it."

Prior to joining CHORI, Wen-Shu Wu, PhD,was a principal investigator at the Center of Biomedical Research Excellence in Stem Cell and Progenitor Cell Biology, Center for Molecular Medicine, Main Medical Center Research Institute, and an assistant professor of the Program in Cell, Molecular and Developmental Biology, the Sackler School of Graduate Biomedical Sciences at Tufts University School of Medicine. Dr. Wu received his Ph.D. degree in cancer biology from the University of Texas MD Anderson Cancer Center, Houston, TX in 2001 and pursued his postdoctoral training at Dana-Farber Cancer Institute/Harvard Medical School.

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Thursday, May 17, 2012 12:49 PM

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