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The Big Picture
Active Clinical Studies at Children's Hospital & Research Center at Oakland

By Principal Investigator:
Principal Investigator Title IRB#:
James, Ellen PhD PNP Pituitary Iron Deposition in B Thalassemia 2006-068
Jawaheer, Damini PhD Investigating the Influence of Pregnancy on Rheumatoid Arthritis Disease Activity 2009-053
Jawaheer, Damini PhD Mapping of the Genes Involved in Treatment Responses Among Rheumatoid Arthritis Patients 2009-086
Jawaheer, Damini PhD Gender differences in outcomes and genetic associations of Rheumatoid Arthritis 2009-087
Kanathezhath, Bindu MD A Phase I Trial of Monoclonal Antibody HGS-ETR2 (Lexatumumab) With or Without Interferon Gamma in Patients with Refractory Pediatric Solid Tumors (P6981) 2009-071
Kelly, Patrick MD Collecting of Umbilical Cord Blood for Use in Unrelated Bone Marrow Transplant 1996-006
Kelly, Patrick MD Collecting of Umbilical Cord Blood for Use in Related Bone Marrow Transplant or Gene Therapy Research in Sickle Cell Disease 1998-025
Kim, Sunghoon MD Surgical Ligation of Patent Ductus Arteriosus and Its Complications at Children's Hospital & Research Center Oakland 1950-005
Kim, Sunghoon MD Electrolyte Expression of Patients with Pyloric Stenosis with Advent of Early Detection with Ultrasound 2005-098
King, Janet PhD An Evaluation of Dietary Zinc Requirements for the Elderly 2005-075
King, Janet PhD Dietary Glycemic Load and Metabolism in Obese Pregnant Women 2005-080
Krauss, Ronald M. MD Genetic Influences on Response to Variations in Dietary Fat in Humans (MM6363) 1988-009
Krauss, Ronald M. MD Effects of Altered Dietary Macronutrient Composition and Weight Loss on Metabolic and Genetic Features of Atherogenic Lipoprotein Phenotype 2000-048
Krauss, Ronald M. MD Hypertension and Ramipril Pharmacogenetic Study (HARP), Pharmacogenetic Network for Cardiovascular Risk Therapy 2002-031
Krauss, Ronald M. MD Cholesterol and Pharmacogenetic Study (CAPS), Pharmacogenetic Network for Cardiovascular Risk Therapy 2002-032
Krauss, Ronald M. MD Blood Donations for Lipoprotein (MM2357) 2002-073
Krauss, Ronald M. MD The Effects of Normalizing Adiposity on Atherogenic Lipoproteins in Subjects with ALP (Atherogenic Lipoprotein Profile) on a High Dairy Fat Diet (MM6676) 2003-088
Krauss, Ronald M. MD A Randomized, Double-Blind, Placebo-Controlled 2-Period Crossover Study to Evaluate the Effects of Ezetimibe on the Postprandial Lipoprotein Response in Patients with Primary Hypercholesterolemia (MM9384) 2004-110
Krauss, Ronald M. MD MM7746: Pharmacogenetic Investigation of the Lipid Lowering and Anti-Inflammatory Properties of Pravastatin: A PRINCE Ancillary Study NIH Grant U01 HL69757 Pharmacogenomics and Risk of Cardiovascular Disease 2004-067
Krauss, Ronald M. MD Personalized Medicine Research Project Clinical Research Center NIH Grant U01 HL69757 Pharmacogenomics and Risk of Cardiovascular Disease (MM7673) 2004-069
Krauss, Ronald M. MD A Randomized, Double-Blind, Placebo-Controlled, 2-Period, Crossover Study to Evaluate the Effects of Ezetimibe on the Plasma Appearance of 7-Ketocholesterol after an Oral Bolus in Patients with Primary Hypercholesterolemia 2006-040
Krauss, Ronald M. MD A Comparison of Energy Efficiency in Individuals with Atherogenic Lipoprotein Profile (ALP) versus Healthy Normolipidemic Individuals, or The Energy Efficiency Pilot Study (MM9733) 2006-062
Krauss, Ronald M. MD The Effects of Increased Dietary Protein Intake on Insulin Sensitivity in Stable Weight Individuals, Independent of Dietary Content of Carbohydrate and Saturated Fat 2006-097
Krauss, Ronald M. MD Genetic Susceptibility to Obesity-Related Dyslipidemia in African Americans, or the GOLD-A (Genetics of Lipid Disorders) Study 2007-021
Krauss, Ronald M. MD The Genetics of Lipid Disorders (GOLD) Recruitment Base 2007-024
Krauss, Ronald M. MD Lipoprotein Effects of Substituting Beef protein for Carbohydrate 2007-068
Krauss, Ronald M. MD Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake 2008-063
Krauss, Ronald M. MD A Meta-Analysis of Prospective Cohort Studies Evaluating the Association of Saturated Fat with Cardiovascular Disease 2008-070
Krauss, Ronald M. MD

Changes in LDL and HDL with increased intake of saturated fat from dairy foods in individuals with atherogenic dyslipidemia and LDL subclass pattern B

2008-092
Krauss, Ronald M. MD Effect of Age on Cholesterol Homeostasis 2009-032
Krauss, Ronald M. MD Effects of Resistant Starch on Lipid and Glucose Metabolism in Insulin Resistance 2009-054
Kuypers, Frans PhD Physiologic Significance of Membrane Phospholipid Asymmetry 1990-031
Kuypers, Frans PhD Examination of Small Blood Vessel Structure and Flow Parameters in Sickle Cell Disease (SCD) by Noninvasive Computer Assisted Intravital Microscopy 2003-056
Kuypers, Frans PhD Use of Discard Samples without Informed Consent 2004-032
Lal, Ashutosh MD Treatment of Children with Thalassemia Major Using Umbilical Cord Blood Stem Cells from Unrelated Donors (PCRC 1579) 2004-056
Lal, Ashutosh MD Biomarkers of Impaired Nutrition in Childhood Obesity 2005-079
Lal, Ashutosh MD Pilot Study of Antioxidant Supplementation with Alpha-Lipoic Acid and Acetyl-L-Carnitine in Thalassemia and Sickle Cell Anemia 2006-031
Lal, Ashutosh MD Evaluation of Mitochondrial Function in Disorders of Iron 2006-086
Lal, Ashutosh MD Retrospective review of the natural history of hemoglobin H disease 2008-055
Lammer, Edward MD The Muscatine Study 2001-029
Lammer, Edward MD Clinical and Genetic Linkage of Lacrimo-Auriculo-Dento-Digital (LADD) Syndrome 2002-063
Lammer, Edward MD CGH Microdelation Array Analysis and Orofacial Clefts 2004-088
Lammer, Edward MD Oral Clefts, Smoking & Variation of Toxin Biotransformation 2005-074
Lammer, Edward MD Gastroschisis: Genetic and Nutritional Risks 2008-024
Lammer, Edward MD California Study of Birth Defect Causes (Project 99-04-03) 2009-022
Lammer, Edward MD Genetic Factors Influencing Spina Bifida 2009-035
Lammer, Edward MD FOXE1 genetic variants and orofacial clefts 2009-046
Lee, Brian MD A Prospective, Randomized Trial Comparing the Efficacy of Anidulafungin and Voriconazole in Combination to that of Voriconazole Alone When Used For Primary Therapy of Proven or Probable Invasive Aspergillosis (A8851009) 2008-043
Lee, Brian MD A Prospective, Open-Label Study to Assess the Pharmacokinetics, Safety and Efficacy of Anidulafungin When Used to Treat Children With Invasive Candidiasis, Including Candidemia (A8851008) 2008-046
Lee, Brian MD An Evaluation of the Safety, Efficacy and Pharmacokinetics of Daptomycin in Pediatric Subjects Aged Seven to Seventeen Years with Complicated Skin and Skin Structure Infections Caused by Gram-Positive Pathogens 2008-058
Leung, Christine MSW Child Sexual Abuse: Factors Influencing When Guardians Seek Medical Services 2005-030
Lifton, Richard MD, PhD Genetic Studies of Electolyte Impalances and Mineral Metabolism 2004-073
Liu, Jiang PhD Human Fetal Eyes 2005-042
Lovette, Bonnie RN PNP MS Preventing "Backovers" and Other Non-Traffic Motor Vehicle Injuries to Children 2005-067
Lucas, Alex PhD Immunity to Meningocooccal Polysaccharide-Conjugate Vaccine (Menactra) 2005-032
Lucas, Alex PhD Vaccine Immunity Following Splenectomy 2009-079
Lucas, Alex PhD Molecular Ontogeny of Human Antibody Repertoires 2009-083
Lubin, Bert MD Pilot Study for Volunteer Cord Blood Banking for Support of Unrelated Stem Cell Recipients 2004-011
Lubin, Bert MD Health and Biomedical Science for Middle School Students 2008-069
Mainwaring, Richard, MD Anomalous Aortic Origin of a Coronary Artery (AAOCA) in Pediatric and Young Adult Patients: A New Study by the Congenital Heart Surgeons’ Society. 2009-090
Martin, David MD Epigenomic assessment of human monocytes 2008-042
Martin, Kenneth MD Natural History of Filum Terminale Cyst: a Retrospective Review 2009-042
Matsunaga, Alison MD The Treatment of Factor XIII Deficiency using Fibrogammine P 1995-004
Matsunaga, Alison MD Universal Data Collection (UDC) 1998-007
Matsunaga, Alison MD The Epidemiology of Diamond Blackfan Anemia:  The Diamond Blackfan Anemia Registry 2006-078
Matsunaga, Alison MD A Prospective, Multicenter, Open-label, Phase 3B Study of Human Plasma-Derived Factor XIII Concentrate in Subjects with Congenital Factor XIII Deficiency 2009-039
McCance-Katz, Elinore MD, PhD Disulfiram Interactions With HIV Medications: Clinical Implications 2009-012
Meade, Kelly, MD Study of African Americans, Asthma, Genes and Environments (SAGE) 2009-017
Meade, Kelly, MD Multimedia Asthma Self-Management Program 2009-033
Miaskowski, Christine, RN, PhD Symptom Clusters in Pediatric Oncology Patients 2008-061
Michlitsch, Jennifer MD Examining Factors That Influence Clinical Trial Participation Among Newly Diagnosed Oncology Patients 2009-013
Mietus-Snyder, Michele  MD Stress, Inflammation, and the Metabolic Syndrome 2006-052
Mietus-Snyder, Michele  MD Healthy Hearts Clinic Research Database 2009-038
Montelius, Lynn MS PhD Smoking, Poor Vitamin Nutriture and Damage to Sperm DNA 2003-044
Morrell, Rose Ellen MD North American Pediatric Renal Transplant Cooperative Study 2004-008
Morrell, Rose Ellen MD A Pilot Study of 24 Hour Blood Pressure Monitoring in Pediatric Patients with a BMI above the 95th Percentile and a Clinic Blood Pressure below the 95th Percentile. 2008-045
Morrell, Rose Ellen MD A Multicenter, Double-blind, Randomized Study Evaluating De Novo Weekly and Once Every 2 Week Darbepoetin alfa Dosing for the Correction of Anemia in Pediatric Subjects With Chronic Kidney Disease Receiving and Not Receiving Dialysis 2008-080
Morris, Claudia MD Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial 2000-008
Morris, Claudia MD Pulmonary Function in Sickle Cell Disease and Thalassemia 2002-067
Morris, Claudia MD The Role of Arginase Activity and Limited Arginine Bioavailability in Asthma 2003-024
Morris, Claudia MD A Multicenter, Randomized, Double-Blind Study Comparing the Clinical Effects of Intravenous Montelukast with Placebo in Pediatric Patients (Ages 6-24 Years) with Acute Asthma (Protocol 301) 2005-083
Morris, Claudia MD Parallel Pilot Series of Oral Arginine and Oral Sildenafil for the Treatment of Pulmonary Hypertension in Thalassemia with Controls 2008-044
Morris, Claudia MD GLUTAMINE THERAPY FOR HEMOLYSIS-ASSOCIATED PULMONARY HYPERTENSION 2008-059

Revised: February 26, 2010 9:13 AM

© 2005 Children's Hospital Oakland Research Institute
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