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The Big Picture
Active Clinical Studies at Children's Hospital & Research Center at Oakland

By Principal Investigator:
Principal Investigator Title IRB#:
James, Ellen PhD PNP Pituitary Iron Deposition in B Thalassemia 2006-068
Jasik, Carolyn  MD Establishment of the Pediatric Obesity Weight Evaluation Registry (POWER):  A Retrospective Chohort Study of Children and Adolescents Presenting  For Weight Management form 2009 Through 2010. 2012-042
Jawaheer, Damini PhD Gender differences in outcomes and genetic associations of Rheumatoid Arthritis 2009-087
Joe, Priscilla  MD A Randomized Clinical Trial of Therapeutic Hypothermia during Transport for HIE: Device Regulated Cooling versus Standard Practice 2012-023
Jones, Mary D. MD, MPH Sources of Variation in Rett Syndrome and MECP2 Disorders 2012-074
Kanathezhath, Bindu MD A Study of Thiol Redox Status in Allogeneic Transplantation to Determine if it can be Predictive of Graft Versus Host Disease 2011-072
Kelly, Patrick MD Collecting of Umbilical Cord Blood for Use in Unrelated Bone Marrow Transplant 1996-006
Kelly, Patrick MD Collecting of Umbilical Cord Blood for Use in Related Bone Marrow Transplant or Gene Therapy Research in Sickle Cell Disease 1998-025
Kim, Sunghoon MD Surgical Ligation of Patent Ductus Arteriosus and Its Complications at Children's Hospital & Research Center Oakland 1950-005
Kim, Sunghoon MD Electrolyte Expression of Patients with Pyloric Stenosis with Advent of Early Detection with Ultrasound 2005-098
King, Janet PhD RD An Evaluation of Dietary Zinc Requirements for the Elderly 2005-075
King, Janet PhD RD Dietary Glycemic Load and Metabolism in Obese Pregnant Women 2005-080
King, Janet PhD RD Effect of Animal Source Food Supplement Prior to and During Pregnancy on Birth Weight and Prematurity in Rural Vietnam 2010-068
King, Janet PhD RD The Role of Zinc in Effective Treatment of Childhood Tuberculosis 2010-077
King, Janet PhD RD Evaluating Novel Biomarkers of Zinc Status 2011-011
King, Janet PhD RD Postprandial Response to Almond Consumption in Pregnant Women 2011-061
King, Janet PhD RD The Effects of Ethnicity on the Distribution and Amount of Body Fat 2012-045
Krauss, Ronald M. MD Genetic Influences on Response to Variations in Dietary Fat in Humans (MM6363) 1988-009
Krauss, Ronald M. MD Effects of Altered Dietary Macronutrient Composition and Weight Loss on Metabolic and Genetic Features of Atherogenic Lipoprotein Phenotype 2000-048
Krauss, Ronald M. MD Hypertension and Ramipril Pharmacogenetic Study (HARP), Pharmacogenetic Network for Cardiovascular Risk Therapy 2002-031
Krauss, Ronald M. MD Cholesterol and Pharmacogenetic Study (CAPS), Pharmacogenetic Network for Cardiovascular Risk Therapy 2002-032
Krauss, Ronald M. MD Blood Donations for Lipoprotein (MM2357) 2002-073
Krauss, Ronald M. MD The Effects of Normalizing Adiposity on Atherogenic Lipoproteins in Subjects with ALP (Atherogenic Lipoprotein Profile) on a High Dairy Fat Diet (MM6676) 2003-088
Krauss, Ronald M. MD A Randomized, Double-Blind, Placebo-Controlled 2-Period Crossover Study to Evaluate the Effects of Ezetimibe on the Postprandial Lipoprotein Response in Patients with Primary Hypercholesterolemia (MM9384) 2004-110
Krauss, Ronald M. MD MM7746: Pharmacogenetic Investigation of the Lipid Lowering and Anti-Inflammatory Properties of Pravastatin: A PRINCE Ancillary Study NIH Grant U01 HL69757 Pharmacogenomics and Risk of Cardiovascular Disease 2004-067
Krauss, Ronald M. MD Personalized Medicine Research Project Clinical Research Center NIH Grant U01 HL69757 Pharmacogenomics and Risk of Cardiovascular Disease (MM7673) 2004-069
Krauss, Ronald M. MD The Effects of Increased Dietary Protein Intake on Insulin Sensitivity in Stable Weight Individuals, Independent of Dietary Content of Carbohydrate and Saturated Fat 2006-097
Krauss, Ronald M. MD The Genetics of Lipid Disorders (GOLD) Recruitment Base 2007-024
Krauss, Ronald M. MD Lipoprotein Effects of Substituting Beef protein for Carbohydrate 2007-068
Krauss, Ronald M. MD

Changes in LDL and HDL with increased intake of saturated fat from dairy foods in individuals with atherogenic dyslipidemia and LDL subclass pattern B

Krauss, Ronald M. MD Effects of Resistant Starch on Lipid and Glucose Metabolism in Insulin Resistance 2009-054
Krauss, Ronald M. MD

Effects of a Modified Lower Carbohydrate, Higher Fat DASH Diet Plan on Plasma Lipids, Lipoprotein Particle Size, and Blood Pressure in Healthy Adults

Krauss, Ronald M. MD Saturated Fat and Protein Effects on Atherogenic Dyslipidemia 2011-041
Krauss, Ronald M. MD Relation of diet to heart disease risk factors in children 2011-047
Krauss, Ronald M. MD Effects of Almond Intake on Atherogenic Dyslipidemia of the Metabolic Syndrome 2012-011
Kuperman, Rachel, MD Task-Evoked Changes In The Electrocorticogram In Epilepsy Patients Undergoing Invasive Electrocorticography And Cortical Mapping For The Surgical Treatment Of Intractable Seizures 2011-017
Kuperman, Rachel, MD Efficacy of Intravenous Levetiracetam in the Treatment of Neonatal Seizures 2011-075
Kuperman, Rachel, MD Eye-com Biosensor as a Seizure Detector 2011-088
Kuperman, Rachel, MD Topical Rapamycin to Erase Angiofibromas in TSC -- Multicenter Evaluation of Novel Therapy Phase II TREATMENT Trial 2012-026
Kuperman, Rachel MD Fast Frequency Oscillations in Infants 2012-068
Kuperman, Rachel MD Eye-com Biosensor as a Seizure Detector 2013-001
Kuypers, Frans PhD Physiologic Significance of Membrane Phospholipid Asymmetry 1990-031
Kuypers, Frans PhD Examination of Small Blood Vessel Structure and Flow Parameters in Sickle Cell Disease (SCD) by Noninvasive Computer Assisted Intravital Microscopy 2003-056
Kuypers, Frans PhD Use of Discard Samples without Informed Consent 2004-032
LaBeaud, Desiree, MD Comparison of Mild and Severe Pandemic H1N1 Cases at Children's 2010-052
LaBeaud, Desiree, MD Epidemiological Study of Persons with Intense Exposure to Ruminants for Rift Valley Fever Virus Infection 2011-078
LaBeaud, Desiree, MD The Burden of Chikungunya and Dengue Transmission, Infection and Disease in Kenya 2013-023
Lal, Ashutosh MD Biomarkers of Impaired Nutrition in Childhood Obesity 2005-079
Lal, Ashutosh MD Evaluation of Mitochondrial Function in Disorders of Iron 2006-086
Lal, Ashutosh MD Determinants Of Annual Transfusion Volume In Thalassemia Major And Sickle Cell Disease Patients On Chronic Red Blood Cell 2011-054
Lal, Ashutosh MD Spectrum of Iron Deficiency Anemia at Children's Hospital & Research Center at Oakland 2012-022
Lal, Ashutosh MD CoSense™ CO Monitor for the Measurement of  End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis 2012-064
Lammer, Edward MD CGH Microdelation Array Analysis and Orofacial Clefts 2004-088
Lammer, Edward MD Gastroschisis: Genetic and Nutritional Risks 2008-024
Lammer, Edward MD California Study of Birth Defect Causes (Project 99-04-03) 2009-022
Lammer, Edward MD Genetic Factors Influencing Spina Bifida 2009-035
Lammer, Edward MD FOXE1 genetic variants and orofacial clefts 2009-046
Lammer, Edward MD Genes, Environmental Exposures, and Hypospadias 2010-056
Lammer, Edward MD Metabolic Genetics of Cleft Lip 2011-030
Lammer, Edward MD Genetic Investigations of Congenital Heart Defects 2012-012
Lammer, Edward MD Chromosomal microdeletions causing heart defects 2012-030
Latronica, Cornelia, MD Effect of Vaso-Occlusive Pain Episodes and other Variables on Tricuspid Regurgitant Jet Velocity as a Proxy for Pulmonary Hypertension in Pediatric Sickle Cell Disease Patients. 2010-095
Latronica, Cornelia, MD Emergency Department Bedside Ultrasound Diagnosis of Constipation in Children 2011-062
Leibovich, Sara  MD Intracellular Magnesium and Calcium in Acute Asthma 2013-002
Long, Dayna  MD iScreen: Evaluating Mobile Technology as a Tool to Elicit Social Determinants of Health 2013-013
Long, Katharine MD Has the Increasing use of Computed Tomography Lowered the Negative Appendectomy Rate at Children's Hospital & Research Center Oakland? 2012-017
Lovette, Bonnie RN PNP MS Preventing "Backovers" and Other Non-Traffic Motor Vehicle Injuries to Children 2005-067
Lucas, Alex PhD Molecular Ontogeny of Human Antibody Repertoires 2009-083
Lucas, Alex PhD Analysis of Immune Receptor Diversity and Clonality in Response to Meningococcal Vaccination 2010-097
Lubin, Bert MD Health and Biomedical Science for Middle School Students 2008-069
Madsen, Kristine MD, MPH The Potentially Addictive Properties of Soda: A Feasibility Study 2013-016
Mainwaring, Richard, MD Anomalous Aortic Origin of a Coronary Artery (AAOCA) in Pediatric and Young Adult Patients: A New Study by the Congenital Heart Surgeons’ Society. 2009-090
Mansour, Karim  MD Assessing the utility of urine culture testing in febrile infants with bronchiolitis. 2012-081
Marbin, Jyothi  MD INFANT-AVICA: Individualized Therapy for Asthma in Toddlers--Acetaminophen Vs. Ibuprofen in Children with Asthma 2012-055
Marsh, Anne MD Association of Cell-Derived Microparticles with Osteonecrosis of the Femoral Head in Sickle Cell Disease 2011-083
Matsunaga, Alison MD The Epidemiology of Diamond Blackfan Anemia:  The Diamond Blackfan Anemia Registry 2006-078
Matsunaga, Alison MD Severe Chronic Neutropenia International Registry 2011-006
Matsunaga, Alison MD The American Thrombosis and Hemostasis Network (ATHN) 2011-091
McCance-Katz, Elinore MD, PhD Disulfiram Interactions With HIV Medications: Clinical Implications 2009-012
Meade, Kelly, MD Study of African Americans, Asthma, Genes and Environments (SAGE) 2009-017
Meade, Kelly, MD APRIL-OCELOT: Azithromycin for Preventing the Development of Upper Respiratory Tract Illness into Lower Respiratory Tract Illness- Oral Corticosteroids for Treating Episodes of Significant Lower Respiratory Tract Symptoms in Children 2011-005
Miaskowski, Christine, RN, PhD Symptom Clusters in Pediatric Oncology Patients 2008-061
Michlitsch, Jennifer MD Defibrotide for Patients with Hepatic Veno-Occlusive Disease (VOD): A Treatment IND Study 2010-016
Michlitsch, Jennifer MD An Open-Label Treatment Protocol for the Use of Voraxaze as Adjunctive Treatment for Patients Experiencing or at Risk of Methotrexate Toxicity (PR001-CLN-pro016) 2011-023
Mietus-Snyder, Michele  MD Stress, Inflammation, and the Metabolic Syndrome 2006-052
Mietus-Snyder, Michele  MD Healthy Hearts Clinic Research Database 2009-038
Morrell, Rose Ellen MD North American Pediatric Renal Transplant Cooperative Study 2004-008
Morris, Claudia MD Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial 2000-008
Morris, Claudia MD Pulmonary Function in Sickle Cell Disease and Thalassemia 2002-067
Morris, Claudia MD Parallel Pilot Series of Oral Arginine and Oral Sildenafil for the Treatment of Pulmonary Hypertension in Thalassemia with Controls 2008-044

Revised: May 13, 2013 1:06 PM

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