| CHORI SERVICES |
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| Cell Sorting Facility |
| Elemental Analysis Facility |
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| Mass Spectrometry Laboratory |
| Microscope & Imaging Facility |
| Molecular Diagnostics |
| Sibling Donor Cord Blood Program |
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Office Hours:
9:00 am - 5:00 pm (E.S.T) Phone: 1-866-835-0966 Please let us know if you are interested in learning more about our program. |
1. Locatelli F, Rocha V, Reed W, Bernaudin F, Ertem M, Grafakos S, Brichard B, Li X, Nagler A, Giorgiani G, Haut PR, Brochstein JA, Nugent DJ, Blatt J, Woodard P, Kurtzberg J, Rubin CM, Miniero R, Lutz P, Raja T, Roberts I, Will AM, Yaniv I, Vermylen C, Tannoia N, Garnier F, Ionescu I, Walters MC, Lubin BH, Gluckman E. Related umbilical cord blood transplant in patients with Thalassemia and Sickle Cell Disease 2003 Blood March 15.
* This study analyzed 44 patients given allogeneic related cord blood transplantation for either thalassemia or sickle cell disease. No patient died and 36 out of 44 children remain disease-free, with a median follow-up of 24 months. At the time of submission of this manuscript 85% of the patients appeared to be cured of their disease. Four patients experienced grade II acute graft vs. host disease (GVHD); only 2 out of the 36 patients at risk developed limited chronic GVHD. Related cord blood transplants (CBT) for hemoglobinopathies offer an excellent probability of success and are associated with a low risk of GVHD. Banking of cord blood and consideration of cord blood donor transplant should be given for children with sickle cell anemia and thalessemia.
2. Reed W,
Smith R, Dekovic F, Lee JY, Saba JD, Trachtenberg E, Epstein J, Haaz S,
Walters MC, Lubin BH. Comprehensive banking of sibling donor cord blood
for children with malignant and nonmalignant disease. 2003 Blood Jan 1;101(1):351-7.
* This report describes the initial experience of
the CHORI Sibling Donor Cord Blood Program in the collection of sibling
donor cord blood units from remote sites and their use in cord blood transplantation.
© 2005 Children's Hospital Oakland Research Institute
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