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Children's Global Health Initiative
Additional Clinical Services & Translational Research Projects
Across the Globe

Africa

Ethiopia

Translational Research
Deborah Dean, MD, MPH, works on vaccine development for trachoma, the leading cause of preventable blindness in the world today. It is estimated by the World Health Organization (WHO) that over 9 million people are blind from this disease and 150 million at risk for blindness. Dr. Dean is a member of the WHO Global Alliance to Eliminate Blinding Trachoma.

Kenya

Clinical Services
Karen Ann Hardy, MD works with the Latter-Day Saints church in Nairobi, Kenya to provide much needed clinical services to children and their families in need.

Translational Research
Angelle Desiree LaBeaud, MD, MS, has three different translational research projects underway in Kenya to investigate Rift Valley Fever, a devastating disease transmitted by mosquitoes. Dr. LaBeaud's work will help to indentify innate immune factors in host susceptibility to Rift Valley Fever, help identify potential diagnostic tools that can clearly identify individuals suffering from the fever, and investigate the effects of polyparasitism (infections from multiple parasites) on infant vaccine response.

Frans Kuypers, PhD has ongoing translational research outreach with a variety of hemoglobinopathy programs in Africa. Along with colleague, Carolyn Hoppe, PhD, Dr. Kuypers participated in the opening of the first national sickle center to be established in Benin, West Africa, in 2009. In 2010, Drs. Kuypers and Hoppe participated in an international meeting to establish international collaborations in Ghana to combat Sickle Cell Disease.

Nigeria

Clinical Services
Olajire Idowu, MD, from Lagos, Nigeria, often travels to Africa to invite Nigerian doctors to visit Children's Hospital. His personal goal is to help provide adequate healthcare systems in Africa.

Dr. Idowu, Katie Sabato, PRT, and several others, including Ziad Saba, MD, went on the group's first medical mission to Nigeria in 2002 to perform some training sessions with Nigerian clinicians. In 2006 they returned to Nigeria with Jonah Odim, MD, PhD and brought needed equipment, including a powerful generator and a heart/lung machine, which helped to keep patients alive during long cardio-thoracic surgical procedures. They trained people to keep those and other key machines running long after the medical team returned to California.

Anu Agrawal, MD, and Kara Dubray, MD, traveled to Lesotho from 2007 through 2008 and is also planning to travel to Botswana in August 2011 to help provide services that are comprehensive in scope, primary and specialty medical care, and social service needs of HIV-infected infants, children, and families. Most HIV-infected children are under the age of 5 and are treatment-naive. Collaborative education and training activities include development of curricula on pediatric health and HIV/AIDS for health professionals, short-term U.S.-Africa exchange fellowships, and long-term training for African health professionals.

Ziad Saba, MD, participates in many medical aid missions in Nigeria.

Herbert Schreier, MD, guest lectured in several countries such as Germany, Denmark, Norway, Albania, Turkey and Canada. He consults a group at the human rights center and the University of California, Berkeley Law School developing guidelines for prevention and treatment of sexual abuse of women and children in Africa. According to the National Mental Health Association, 1 in 5 children have some sort of an emotional or behavioral disorder. Of these children, 10 percent suffer from serious emotional disturbances. In addition, nearly 70 percent fail to receive any mental health assistance.

Anna Usowicz, MD, is a team member for humanitarian aid missions to Africa, advising on state-of-the-art neonatal care.

Senegal and Mali

Translational Research
Fernando E. Viteri, MD, ScD has built strong collaborative relationships in translational research in his area of specialty, iron nutrition, and is a visiting scientist with INSERM.

Sub-Saharan Africa

Translational Research
Dan Granoff, MD, helped create a vaccine and business plan that ultimately became the WHO/PATH Meningitis Vaccine Project. Prior to Dr. Granoff's work, although there was the knowledge base available to develop a meningitis vaccine, there was no infrastructure in place to do so. As a result of his translational research efforts, and in collaboration with the Gates Foundation, WHO and PATH, the development of a vaccine is underway that will help stop this decimating disease that can kill whole villages at a time.

Uganda (A Focused Country Program)

Clinical Services
In July, 2010, our doctors and nurses journeyed to Mbarara, Uganda. They provided 700 pounds of medical supplies and medical care, but their primary objective was to train medical staff and help launch Holy Innocents Children's Hospital Uganda (HICH), the country's first-ever children's hospital. The team helped to install a neonatal unit, a community nutrition study, and emergency medicine triage protocols. After six months of opening, HICH received national accreditation. The new hospital will play an important role in the effort to combat the country's excessively high infant mortality rate. In Uganda, 1 in 7 children die before the age of 5. Best of all, the patient mortality rate has decreased to less than one-half percent since HICH opened.

Mary Coleman, MD, MPH, organized a trip to Mbarara, Uganda and provided developmental screening and assessment. This later grew into a nutrition surveillance project, which included home visits, nutrition surveys, and nutrition assessments at preschool and elementary schools.

Chuck Clemons, MD, provides emergency care triage and alternative strategies to deliver medicine and fluid when IV access is not available.

Priscilla Joe, MD, and neonatology nurses Elizabeth Schaub, RN, and Rini Kwok, RN perform and train neonatal resuscitation, feeding, and nutrition guidance at HICH.

CGHI's next visit to Mbarara, Uganda will focus on Hematology/ Oncology, IT, HIV, and Hospice, along with ongoing efforts in infectious disease and malaria and hospital infrastructure (water, IT and power).

Zambia

Clinical Services
Chuck Clemons, MD, teaches in the Department of Pediatrics at the University Teaching Hospital (UTH) in Lusaka, Zambia. They support AIDS orphans in Zambia and try to improve education and capacity at UTH.

 

Asia

China

Clinical Services
Karen Ann Hardy, MD has ongoing work with the Health Alliance International (HAI) in an effort to help provide much needed clinical services.

Japan

Translational Research
Ronald Krauss, MD, is part of an international consortium for the study of statin pharmacogenetics that includes groups from Taiwan, Tokyo (Riken Institute) and University of Dundee, Scotland. The international group will be conducting translational research to help determine what genetic factors make statin drugs, which are used to prevent heart disease, more or less effective.

Vasanthy Narayanaswami, PhD, is conducting translational research to study oxidative protein and lipid modification in normal and disease states, in collaboration with Graduate School of Agricultural Sciences, Nagoya University, Nagoya, Japan.

Elizabeth Theil, PhD, studies ferritn gene transcriptional regulation by heme and protein repressor, bach1, in collaboration with Kazuhiko Igarashi, MD, Prsf. Intgernal Medicine and Hematology, Tohhoku University Medical School, Tohoku, Japan.

Fernando Viteri, MD, ScD, holds a Coordinator position at the International Iron Nutrition Programme, United Nations University.

India

Clinical Services
Bertram H. Lubin, MD provides clinical services in the field of hematology, providing cord blood banking.

Anna Usowicz, MD, is a team member for humanitarian aid missions to India, advising on state-of-the-art neonatal care.

Translational Research
Deborah Dean, MD, MPH is using in silico research for studying the pathways related to the pathogenesis of different Chlamydiaceae diseases, in collaboration with Cellworks, Bangalore.

Frans Kuypers, PhD has strong relations with hemoglobinopathy programs in India. In 2007 he helped to organize an international meeting with the University of Varanasi in India on genetic disorders with a focus on hemoglobinopathies.

Janelle Noble, PhD is part of the Type 1 Diabetes Genetics Consortium (T1DGC), which is an international effort to collect a very large cohort of samples with the goal of finding genetic susceptibility factors for Type 1 Diabetes.

Julie Saba, MD, PhD researches drosophila genetics, in collaboration with the National Centre for Biological Sciences, Tata Institute of Fundamental Research, Dr. K. Vijay Raghavan, Senior Professor and Director.

Fernando Viteri, MD, ScD researches iron/folate supplementation in collaboration with the National Institute of Nutrition in India and the Institute of Research for Development, Montpellier, France.

Korea

Translational Research
Janet King, PhD is conducting translational research on zinc metabolism and function in Korean women, in collaboration with the Seoul National University and Hee Young Paik.

Laos

Clinical Services
Karen Ann Hardy, MD works with the Latter-Day Saints church in Laos to provide much needed clinical services to children and their families in need.

Nepal

Translational Research
Deborah Dean, MD, MPH, has two translational research projects in Nepal, one which focuses on trachoma pathogenesis, and deciphering immune and infection factors in the recurrence of trichiasis, in collaboration with Lumbini-Ambika Eye Hospital. The other project evaluates clean water resources and their impact on infectious diseases and health, in collaboration with WaterAid and Seva Foundation.

Vietnam (Northern)

Clinical Services
Richard Cohen, MD primarily teaches radiology at children's hospitals and in some provincial hospitals. He works in collaboration with Project Vietnam and the American Academy of Pediatrics.

Priscilla Joe, MD works with the East Meets West Foundation, Medical/Technical Advisor, Operation Healthy Heart Program, Breath of Life Program, and Phototherapy Pilot Project at the following nine hospitals in Vietnam: Bac Nihn Provincial Hospital; Bac Giang Provincial Hospital; Lang Son Provincial Hospital; Cao Bang Provincial Hospital; Bac Kan Provincial Hospital; National General Hopsital of Thai Nguyen; OBGYN National Hospital of Hanoi; Saint Paul General Hospital, Hanoi; and National Hospital of Pediatrics, Hanoi. Dr. Joe has also helped to create a Newborn Initiative Training Team that provides Neonatal training with Project Vietnam, AAP California Chapter 4 and Khang Hoa Hospital, and Vinh Phuc Hospital, National Hospital Pediatrics, Hanoi. In addition, Dr. Joe leads the Neonatal Training Team and provides Neonatal training at Phu Quoc District Hospital, Rhac Gia Provincial Hospital. She collaborates with Project Vietnam.

Translational Research
Deborah Dean, MD, MPH is studying Trachoma in northern Vietnam, in collaboration with Vietnamese National Institutes of Ophthalmology.

Vietnam (Southern)

Clinical Services
Deborah Dean, MD, MPH collaborates with Tropical Medicine Institute and Hospital.

Scott Hoffinger, MD works in collaboration with the Pediatric Orthopaedic Society of North America as part of the Committee for Orthopaedics in Underdeveloped Regions (COUR) group. The COUR group give lectures, saw cases, and presented at the Hospital for Traumatology and Orthopaedics in Ho Chi Minh City.

Priscilla Joe, MD is an instructor of a Neonatal skills course at the Ho Chi Minh School of Medicine, and leads the Pediatric Transport Program Development at the Nhi-Dong 1 Hospital.

Bertram H. Lubin, MD works in the field of Hematology providing cord blood banking.

Translational Research
Deborah Dean, MD, MPH has two translational research projects in Ho Chi Minh City, one which focuses on C. pneumoniae and TB in lung disease in Ho Chi Minh City, in collaboration with Lung Hospital and District Medical Center, the other which focusses on chlamydial sexually transmitted diseases in Ho Chi Minh City, in collaboration with Dermatovenereal Disease Hospital.

 

Australia

Translational Research
Janelle Noble, PhD is part of the Type 1 Diabetes Genetics Consortium (T1DGC), which is an international effort to collect a very large cohort of samples with the goal of finding genetic susceptibility factors for Type 1 Diabetes.

 

Central America

Belize

Clinical Services
Ziad Saba, MD, participates in many medical aid missions in Belize.

Katie Sabato, PRT, respiratory therapy expert traveled to Belize to help a former Children's Hospital doctor improve conditions at Karl Heusner Hospital.

Honduras

Clinical Services
Arup Roy-Burman, MD, is a co-founder and director of the Roatan Volunteer Pediatric Clinic, in Roatan, Honduras. This non-profit clinic offers one of the only year-round international electives for pediatric residents; see http://www.roatanclinic.org/

 

Europe

Austria

Translational Research
Janelle Noble, PhD is part of the Type 1 Diabetes Genetics Consortium (T1DGC), which is an international effort to collect a very large cohort of samples with the goal of finding genetic susceptibility factors for Type 1 Diabetes.

Belgium

Translational Research
Vasanthy Narayanaswami, PhD is conducting infrared structural analysis of neurological disease involving protein misfolding such as amyloidopathy in Down's syndrome and Alzheimer's disease, in collaboration with Structural Biology & Bioinformatics Center, Universite Libre de Bruxelles, Belgium.

Robert Ryan, PhD is using an application of infrared spectroscopy to the study of lipid associated proteins, in collaboration with Vincent Raussens, Free University Brussels, Belgium.

France

Translational Research
Deborah Dean, MD, MPH offers exchange program for graduate students from the University of Paris to conduct research on trachoma pathogenesis in her lab at Children's Hospital Oakland Research Institute (CHORI).

Fernando Viteri, MD, ScD has two translational research projects in France, one in which he is a member of the International Scientific Surveillance Committee of the study SU.VI.MAX, INSERM/ISTNA/CNAM in the area of iron nutrition. THe other is an iron/folate supplementation study in collaboration with the National Institute of Nutrition in India and the Institute of Research for Development, Montpellier, France.

Germany

Translational Research
Laura Hertel, PhD researches human cytomegalovirus tropism for dendritic and endothelial cells: identification of the viral and cellular determinants and of their mechanisms of action, in collaboration with Christian Sinzger, Institute of Medical Virology, University of Tubingen.

Italy

Translational Research
Dan Granoff, MD, has a variety of translational research projects in Italy in the area of immunology and vaccine development.

Janelle Noble, PhD, has two research projects in Italy, one , in collaboration with Dr. Paolo Pozzili from the University of Rome "La Sapienza," on Italian type 1 diabetes, and the other in collaboration with Ana Maria Vlades Bologna, Italy, on the genetics of autoimmune disease.

Elizabeth Theil, PhD, studies the dynamics of ferritin nanocages and pores by NMR spectroscopy, in collaboration with Ivano Bertin, DSC., Prof of inforganic chemistry and Director Center of Magnetic Resonance, Univerite Firenze, Florence, Italy.

Netherlands

Translational Research
Deborah Dean, MD, MPH, is studying Chlamydial immunogenetics, in collaboration with VU University Medical Center, Amsterdam.

Pieter de Jong, PhD researches gene screening for cleft palate in Nijmegen, Netherlands, in collaboration with Eric Schoenmakers, F.P.M., Assistant Professor, Human Genetics at Radboud University.

Edward Lammer, MD, has two different translational research projects in The Netherlands. The first is a series of collaborative epidemiological studies on folate-related biochemical pathways and folate transport. This study, called Conotruncal defects: genetic and nutritional "risk," is in collaboration with Dr. Henk Blom, Metabolic Unit, Department of Clinical Chemistry, Free University Medical Center, Amsterdam. The second is the CHeartED Project, in which Dr. Lammer serves on the External Advisory Committee for this EU-funded project, under the direction of Professor Antoon FM Moorman, Head of the Department of Anatomy, Embryology & Physiology at Academisch Medisch Centrum (AMC), Amsterdam. The mission of CHeartED is to identify genetic and environmental pathways that can be modified with the goal of reducing preventable cardiovascular malformation incidence. The project includes a genetic association study in individuals with and without cardiovascular malformations born to diabetic mothers, to test whether genetic variants are associated with increased risk for heart defects. A similar study, without prior risk hypothesis, addresses tetralogy of Fallot. These studies will reveal common genetic variants associated with cardiovascular malformations and thus add to existing knowledge on their aetiology. http://www.chearted.eu.

Portugal

Translational Research
Deborah Dean, MD, MPH, is researching chlamydial genomics, in Lisbon, Portugal, in collaboration with the National Institutes of Health.

Republica of Georgia

Clinical Services
Ziad Saba, MD, participates in many medical aid missions in the Republic of Georgia.

Spain

Translational Research
Janelle Noble, PhD, studies on HLA and T1D in Basque, in collaboration with Ramon Bilbao, Bilbao, Spain.

Fernando Viteri, MD, ScD, studies HFE polymorphisms and hemochromatosis in collaboration with the Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain, Unit of Preventive Medicine and Public Health, and is an extraordinary Professor at the University of Navarre, Spain.

Sweden

Translational Research
Edward Lammer, MD researches chromosomal microdeletions causing heart defects, in collaboration with Professor Åke Borg, Department of Oncology, Lund. University. Dr. Borg's lab creates the human chromosomal microdeletion microarrays necessary for this research. The DNA sequences used for creating the microarrays derive from the BACPAC Facility at CHORI under the direction of Dr. Pieter de Jong.

Janelle Noble, PhD, is part of the Type 1 Diabetes Genetics Consortium (T1DGC), which is an international effort to collect a very large cohort of samples with the goal of finding genetic susceptibility factors for Type 1 Diabetes. Trained international scientists in HLA genotyping technology.

Robert Ryan, PhD, studies receptor-ligand interactions, in collaboration with Gunilla Olivecrona, Umeå University, Sweden.

United Kingdom

Translational Research
Deborah Dean, MD, MPH researches researches chlamydial comparative genetics and development of a multilocus sequence typing (MLST) scheme, in collaboration with Imperial College London.

Pieter de Jong, PhD has three research projects in the United Kingdom involving gene targeting to create knock-out alleles of mouse gene lines, in three different collaborations with Professor Allan Bradley, Director, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK, Genome Research Limited, London, UK; Pentao Liu, PhD, Sanger Institute, Hinxton, Cambridge, UK, and William Skarnes, PhD, Sanger Institute, Hinxton, Cambridge, UK.

Ronald Krauss, MD is part of an international consortium for the study of statin pharmacogenetics that includes groups from Taiwan, Tokyo (Riken Institute) and University of Dundee, Scotland.

Janelle Noble, PhD is studying the genetics of susceptibility in osteoarthritis, in collaboration with Dr. Tim Spector at King's College, University of London. In addition, Dr. Noble has an ongoing collaboration with Kathleen Gillespie, Bristol, United Kingdom, and is part of the Type 1 Diabetes Genetics Consortium (T1DGC), which is an international effort to collect a very large cohort of samples with the goal of finding genetic susceptibility factors for Type 1 Diabetes.

Robert Ryan, PhD, researches Amphotericin B Nanodisks in treatment of leishmaniasis, in collaboration with Pascale Kropf, University College London, UK.

Cedric Shackleton, PhD, DSc, researches disorders of steroidogenesis in adults and children; metabolic syndrome, CAH, in collaboration with the Department of Medical Sciences, University of Birmingham, United Kingdom.

 

Middle East

Palestinian Territories

Clinical Services
Ziad Saba, MD, participates in many medical aid missions in Palestinian Territories.

Herbert Schreier, MD, provides foreign consultation on a variety of child psychiatric issues in countries throughout Europe and the Middle East.

 

North America

Canada

Translational Research
Laura Hertel, PhD is researching the identification of the cellular binding partners of two cytomegalovirus-encoded proteins, one potentially involved in viral immunoevasion and one potentially mediating viral capsid interactions with the nuclear envelope. Collaboration with Joseph Mymryk, Departments of Oncology and of Microbiology & Immunology, University of Western Ontario.

Vasanthy Narayanaswami, PhD, is researching axonal degeneration and neuronal survival in Alzheimer's disease, in collaboration with Division of Neuroscience, Department of Pharmacology, University of Alberta, Edmonton, Canada.

Janelle Noble, PhD, is working on DPB1 in Nova Scotia T1D, in collaboration with Andrew Patterson, Toronto, Ontario, Canada.

Robert Ryan, PhD, is researching the hydrodynamic characterization of proteins in solution in collaboration with Cyril M. Kay, Department of Biochemistry, University of Alberta, Edmonton, Canada.

Cuba

Translational Research
In October 2010, Bertram Lubin, MD, Elliott Vichinsky, MD, Frans Kuypers, PhD, and Carolyn Hoppe, MD, visited Cuba for a bilateral meeting on the management of Sickle Cell Disease.

Mexico

Translational Research
Janet King, PhD, & Janelle Noble PhD study maternal nutrition and risk of glucose intolerance in Mexican women, in collaboration with the Institute of Perinatology in Mexico City, Esther Casanueva.

Janelle Noble, PhD is part of the Type 1 Diabetes Genetics Consortium (T1DGC), which is an international effort to collect a very large cohort of samples with the goal of finding genetic susceptibility factors for Type 1 Diabetes. Trained international scientists in HLA genotyping technology.

Fernando E. Viteri, MD, ScD studies iron and folate nutrition in pregnant women and in women of fertile age, in collaboration with the National Institute of Perinatology.

United States

All our scientists work in the United States, most specifically in California, Florida, Massachusetts, Michigan, New York, North Carolina, Pennsylvania, Washington, and Washington DC.

 

Russia

Clinical Services
Karen Ann Hardy, MD, works in collaboration with Heart to Heart.

Translational Research
Vladimir Serikov, MD, PhD, researches derivation and use of adult stem cells in muscle (myodistrophy), skin and bone regeneration, in collaboration with the Institute of Cytology, Russian Academy of Sciences at St. Petersburg, Russia.

 

South America

Argentina

Translational Research
Fernando Viteri, MD, is collaborating in research on community nutritional evaluation of integrated developmental and nutrition interventions, and studies on lead absorption. He is the chairman of the International Scientific Advisory Committee for the Instituto de Desarollo e Investigaciones Pediátricas (IDIP), Hospital Pediátrico de la Provincia de Buenos Aires (Sor María Ludovica) and also collaborates with the University of La Plata, Argentina.

Chile

Translational Research
Elizabeth Theil, PhD studies mechanisms of dietary iron gut absorption from ferritin in collaboration with M. Tulio Nunze, Prof. Biological Sciences, University of Chile, Santiago, Chile.

Ecuador

Translational Research
Deborah Dean, MD, MPH, works on chlamydial infection as a co-factor with human papilloma virus in cervical cancer, in collaboration with Universidad Central del Ecuador, Pontificia Universidad Católica del Ecuador, Quito.

Guatemala

Translational Research
Fernando E. Viteri, MD, ScD, is an invited lecturer at different Universities in the country. He works in collaboration with the National Council of Research and Technology, Guatemala and the University System.

Peru

Translational Research
Janet King, PhD studies the effects of zinc delivered as a fortified food product or a liquid supplement on the growth, morbidity, and plasma zinc concentrations in young Peruvian children, in collaboration with the Bill and Melinda Gates Foundation, and Dr. Kenneth Brown, Professor of Nutrition at The University of California, Davis.

 

 

Revised: Friday, February 14, 2014 4:14 PM

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